First Bowl
When the seven angels who had the seven plagues come out from the Temple of God, they receive from one of the four living
creatures a bowl of God's wrath (Rev 15:6-7), and it appears that each plague is mixed
with each corresponding bowl (Rev 21:9).
The first bowl / plague (Rev 16:2):
1. Poured on the earth.
2. Causes loathsome and malignant sores on people who had the mark of the beast and worshiped his image.
3. Because the surviving human beings are non-Believers (Rev 9:20-21;
13:8, 16-17), most, if not all, human beings are tormented with disfiguring and painful
sores.
In light of the eagle's woe for "those who dwell on the earth" (Rev 8:13;
11:14), the bowl plagues represent the third, last woe, and the only remaining judgments
against those left on earth; they represent the "reaping" by the angel (Rev 14:18-20).
The reaping figuratively speaks of gathering the "ripe" grapes and throwing them into the great wine press of
God's wrath "outside the city" (Rev 14:18-19), which is a reference to the bowl judgments
(Rev 16:1-21). This period of reaping includes the angelic assistance of carrying out Jesus
Christ's judgment at Armageddon, because it is Jesus who treads upon the grapes in the great wine press of God's wrath
(Rev 19:15-21).