When the seven angels who had the seven plagues come out from the Temple of God, they receive from one of
the four living creatures a bowl of God's wrath (Rev 15:6-7), and it
appears that each plague is mixed with each corresponding bowl (Rev 21:9).
The sixth bowl / plague (Rev 16:12):
1. Poured onto the Euphrates River, and it dries up.
2. The drying of the Euphrates River sets in motion the conflict at Armageddon by enabling the
kings from the east to mobilize their troops over land Rev 16:14-16.
In light of the eagle's woe for "those who dwell on the earth" (Rev 8:13;
11:14), the bowl plagues represent the third, last woe, and the only
remaining judgments against those left on earth; they represent the "reaping" by the angel
The reaping figuratively speaks of gathering the "ripe" grapes and throwing them into the great
wine press of God's wrath "outside the city" (Rev 14:18-19), which is a
reference to the bowl judgments (Rev 16:1-21). This period of reaping
includes the angelic assistance of carrying out Jesus Christ's judgment at Armageddon, because it is Jesus who
treads upon the grapes in the great wine press of God's wrath (Rev 19:15-21).