This first woe is placed within a repetition of woes. It is proclaimed with a sense of sadness, almost like a sympathetic sorrow;
but, there is an emphasis, a declaration of condemnation, with the sense of divine judgment of the evil upon the disbelieving world.
Then I looked, and I heard an eagle flying in midheaven, saying with a loud voice, "Woe, woe, woe to those
who dwell on the earth, because of the remaining blasts of the trumpet of the three angels who are about to sound!"
Up until to the fifth trumpet, God's wrath of judgment was not focused on causing physical injury upon human beings;
now the last three trumpets will bring torment and death upon all of mankind on earth.