When the Temple of God opens, revealing the Ark of the Covenant
(Rev 11:19; 15:5;
Ex 40:1-3), the apostle John perceives the appearance of the seven
angels with the seven plagues as a "sign in heaven" that was "great and marvelous," because "in them, the wrath of
God is finished" (Rev 15:1).
The plagues and bowls of God's wrath are significant for the judgments they render; it is a terrible time.
But instead of repenting amidst this great suffering, the people did not fear God, blasphemed His name and failed
to recognize that He was Lord of all. People preferred to follow the "great men of earth" and would be unable to
hear the gospel (Rev 18:23).
Then I heard a loud voice from the temple, saying to the seven angels, "Go and pour out
on the earth the seven bowls of the wrath of God." (Rev 16:1)